10 Things Women Over 40 Need to Know About Estrogen

“Estrogen decline in perimenopause is not steady. It’s a rollercoaster.” – Leslie Duffy

Do you feel like your body changed overnight? Maybe your weight won’t budge, your joints ache, your period is all over the place, or your moods swing like a rollercoaster? Chances are, estrogen is connected to your symptoms.

Most of us were never taught about what estrogen does in our bodies, and by the time we walk into our doctor’s office, it’s already causing chaos. Then, their jargon can leave you feeling lost, dismissed, or even foolish for not knowing what’s going on with your own body.

Today, I’m breaking down 10 things every woman over 40 needs to know about estrogen and, more importantly, what to do about it. You’ll learn what estrogen dominance is, how estrogen and progesterone work like a seesaw, why high stress makes estrogen dominance worse, and how estrogen works as your “juicy hormone” to keep your skin plump, your joints flexible, and your vaginal tissue healthy. We’re also digging into how estrogen affects your bones, metabolism, histamine response, and more, plus the steps you can take right now to start to optimize your hormone health.

By the end of this episode, you’ll be aware of red flags that may signal estrogen imbalance, which action steps to prioritize, and why estrogen matters for more than your cycle. It’s time to stop guessing, start tracking, and feel empowered in this season of life.

Your Takeaways

• Why understanding your hormones and advocating for yourself is essential

• The three types of estrogen and their roles across our life stages

• Common symptoms of estrogen dominance

• How estrogen supports collagen, joint flexibility, and tendon strength

• Estrogen’s role in bone turnover and bone loss prevention

• The impact of low estrogen on vaginal and bladder health

• Estrogen’s effect on metabolism and insulin sensitivity

• How estrogen and progesterone balance each other

• Why ovulation is critical for hormone health

• The rollercoaster of estrogen decline in perimenopause

• Symptoms of high estrogen in perimenopause

• How estrogen impacts histamine and mast cells

• Estrogen detoxification and why liver and gut health are significant

Mentioned in this Episode

Free Resources

Fireproof Your Hormones | A real-life approach to calming inflammation and supporting hormone health: Get Your Free Guide

Tracker + Symptom Checklist | Too many symptoms, not enough answers? Grab this free tracker + symptom checklist to start connecting the dots. Get Your Free Tracker

Articles

• Effect of estrogens on skin aging and the potential role of SERMs

• Estrogen Inhibits Bone Resorption by Directly Inducing Apoptosis of the Bone-resorbing Osteoclasts

• Phytoestrogens protect joints in collagen induced arthritis by increasing IgG glycosylation and reducing osteoclast activation

Ready to go deeper? Explore ways to work with Leslie

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Disclaimer

The content in this podcast and on this website is not a substitute for medical advice from your health care practitioner or your medical team. While I am a licensed healthcare professional, I am not giving you medical advice. This is purely for educational purposes. Please consult your provider for medical guidance specific to you.